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Before you order tramadol online from a certified provider, it is essential to understand the distinction between immediate-release and extended-release formulations. Immediate-release tablets, often starting at a 50 mg dose, are designed for acute pain that requires fast-acting relief, such as sudden injury or short-term post-operative recovery. In contrast, extended-release versions (ranging from 100 mg to 300 mg) are formulated for chronic, long-term conditions like arthritis or persistent back pain that require around-the-clock management. You should never crush, chew, or break an extended-release tablet, as this can cause the entire dose to be released into the bloodstream at once, significantly increasing the risk of a fatal overdose. Always follow your doctor’s specific instructions regarding which formulation is best suited for your diagnosis.